Published Academic Articles Medical Cannabis

Neurobiology of Cannabinoids and Medical Cannabis in Therapeutic Intervention for Multiple Sclerosis: Understanding the Molecular Mechanisms of Action

Book Chapter, 2023

Medical Cannabis in the Treatment of Parkinson’s Disease

Clinical Neuropharmacology, 2023

Licensed Medical Cannabis Use in Gilles de la Tourette Syndrome: A Retrospective Long-term Follow-Up

Cannabis and Cannabinoid Research, May 2023

Clinical Outcome Data of Children Treated with Cannabis-Based Medicinal Products for Treatment Resistant Epilepsy

Neuropediatrics, 2023

Cannabis-Responsive Biomarkers: A Pharmacometabolomics-Based Application to Evaluate the Impact of Medical Cannabis Treatment on Children with Autism Spectrum Disorder

Cannabis and Cannabinoid Research, 2023

Clinical outcome data of chronic pain patients treated with cannabis-based oils and dried flower from the UK Medical Cannabis Registry

Expert Review of Neurotherapeutics, Apr 2023

Transmucosal delivery of the medical Cannabis oil via a nanoemulsion formulation

Journal of Drug Delivery Science and Technology, Jan 2023

Use of Medical Cannabis by Patients With Cancer: Attitudes, Knowledge, and Practice

Journal of Pain and Symptom Management May 2023

The use of medical cannabis concomitantly with immune checkpoint inhibitors in non-small cell lung cancer: A sigh of relief?

European Journal of Cancer Feb 2023

The effect of medical cannabis in inflammatory bowel disease

Expert Review of Gastroenterology & Hepatology Dec 2022

Medicinal cannabis for pain: Real-world data on three-month changes in symptoms and quality of life

Sage Journals 2023

Medical Cannabis Use Patterns for Sleep Disorders in Australia

Nature and Science of Sleep 2023

Medicinal cannabis for psychiatry-related conditions: an overview of current Australian prescribing

Frontiers Pharmacology, June 2023

Sex Differences in the Pharmacokinetics of Cannabidiol and Metabolites Following Oral Administration of a Cannabidiol-Dominant Cannabis Oil in Healthy Adults

Cannabis and Cannabinoid Research 2023

[Tetrahydrocannabinol (THC) in patients with fibromyalgia syndrome (FMS) : A retrospective study of changes in pain, psychometric variables, and analgesic consumption during inpatient interdisciplinary multimodal pain therapy (IMPT)]

Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry

Psychopharmacology 2023

CANNA-TICS: Efficacy and safety of oral treatment with nabiximols in adults with chronic tic disorders

Psychiatric Research 2023

The effect of medical cannabis in inflammatory bowel disease: analysis from the UK Medical Cannabis Registry

Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions

Medication sparing after medical cannabis initiation: A case study of a chronic pain patient in Project Twenty21

The effect of medical cannabis in inflammatory bowel disease: analysis from the UK Medical Cannabis Registry

CBG: A compound with medical potiential

Project CBD November 2022

A large Australian registry demonstrates sustained safety and efficacy of oral medicinal cannabis for at least two years

PLoS ONE November 2022

A large Australian longitudinal cohort registry demonstrates sustained safety and efficacy of oral medicinal cannabis for at least two years

Plos One. November 2022.

CBG: A compound with intriguing medical potential

Project CBD. November 2022

New Developments in Cannabis Medicine – Dr Bonni Goldstein

Interview: Project CBD

Cannabidiol and the Changing Perspective of Epilepsy Drug Discovery

“Is medical cannabis safe for my patients?” A practical review of cannabis safety considerations

European Journal of Internal Medicine. 2021

Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline

BMJ 2021

Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials

BMJ 2021

A Phase 1, Randomised, Placebo‑Controlled, Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of Cannabidiol in Fed Healthy Volunteers

European Journal of Drug Metabolism and Pharmacokinetics. 2020

Antiseizure Effects of Cannabidiol Leading to Increased Peroxisome Proliferator-Activated Receptor Gamma Levels in the Hippocampal CA3 Subfield of Epileptic Rats

Pharmaceuticals (2022)

Improved cognition impairment by activating cannabinoid receptor type 2: Modulating CREB/BDNF expression and impeding TLR-4/ NFκBp65/M1 microglia signaling pathway in D-galactose-injected ovariectomized rats

PLoS ONE (March 2022)

Motor‑like Tics are Mediated by CB2 Cannabinoid Receptor‑dependent and Independent Mechanisms Associated with Age and Sex

Molecular Neurobiology (2022)

Editorial: Tribute to Professor Raphael Mechoulam, The Founder of Cannabinoid and Endocannabinoid Research

Molecules (2022)

New Insights and Potential Therapeutic Targeting of CB2 Cannabinoid Receptors in CNS Disorders

This review addresses recent advances on the role of CB2Rs in neuropsychiatric and neurodegenerative disorders, including, but not limited to, anxiety, depression, schizophrenia, Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD) and addiction. International Journal of Molecular Sciences. (2022)

Detection of Cannabinoid Receptor Expression by Endometriotic Lesions in Women with Endometriosis as an Alternative to Opioid-Based Pain Medication

Results suggest that ovarian endometriotic lesions express CB1 and CB2 receptors, and these lesions may respond to cannabinoids as pain medication. Journal of Immunology Research (2022)

Special Issue Editorial: Cannabinoid signalling in the brain: New vistas

This special issue intends to bring together a series of empirical papers, targeted reviews and opinions from leaders in the field that will highlight the new advances in cannabinoid research. European Journal of Neuroscience (2022)

Vitamin D mitigates diabetes-associated metabolic and cognitive dysfunction by modulating gut microbiota and colonic cannabinoid receptor 1

Targeting gut microbiota by Vit D could be a successful strategy in the treatment of diabetes and associated cognitive deficit. European Journal of Pharmaceutical Sciences (2022)

Neurobiology of cannabinoid receptor signaling

Dialogues in Clinical Neuroscience (2020)

Identification of an Orally Bioavailable, Brain-Penetrant Compound with Selectivity for the Cannabinoid Type 2 Receptor

Molecules (2022)

Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta-analysis

The effectiveness of cannabinoids alone to improve outcomes of CAC remains unclear. Low-quality evidence from both RCTs and NRSIs shows no significant benefits of cannabinoids for weight gain, appetite stimulation, and better quality of life, three important outcomes of cachexia. Journal of Cachexia, Sarcopenia and Muscle (2022)

Clinical management of cannabis withdrawal

This review describes the diagnosis, prevalence, course and management of cannabis withdrawal and highlights opportunities for future clinical research. Addiction Oct 2021

Efficacy and safety of medical cannabinoids in children: a systematic review and meta-analysis

Scientific Reports, Dec 2021

Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms

Cannabis and Cannabinoid Research 2021

The Effects of Cannabis on Female Reproductive Health Across the Life Course

Cannabis and Cannabinoid Research 2021

A Review of Hemp as Food and Nutritional Supplement

Cannabis and Cannabinoid Research 2021

Perceived Efficacy, Reduced Prescription Drug Use, and Minimal Side Effects of Cannabis in Patients with Chronic Orthopaedic Pain

Cannabis and Cannabinoid Research 2021

Motor‑like Tics are Mediated by CB2 Cannabinoid Receptor‑dependent and Independent Mechanisms Associated with Age and Sex

Gorberg V, Borisov V, Greig IR, Pertwee RG, McCaffery P, Anavi-Goffer S. Molecular Neurobiology 2022

Tribute to Professor Raphael Mechoulam, The Founder of Cannabinoid and Endocannabinoid Research

Mauro Maccarrone Molecules 2022

New Insights and Potential Therapeutic Targeting of CB2 Cannabinoid Receptors in CNS Disorders

Kibret BG, Ishiguro H, Horiuchi Y, and Onaivi ES. International Journal of  Molecular Science 2022

Identification of an Orally Bioavailable, Brain-Penetrant Compound with Selectivity for the Cannabinoid Type 2 Receptor

Ospanov M, Sulochana SP, Paris JJ, Rimoldi JM, Ashpole N, Walker L, Ross SA, Shilabin AG, and Ibrahim MA. Molecules 2022

Neurobiology of cannabinoid receptor signaling

Lutz, Beat. Dialogues in Clinical Neuroscience 2020

Expert advice for prescribing cannabis medicines for patients with epilepsy—drawn from the Australian clinical experience

British Journal of Clinical Pharmacology 2022

Detection of Cannabinoid Receptor Expression by Endometriotic Lesions in Women with Endometriosis as an Alternative to Opioid-Based Pain Medication

Sarah Allam, S., Paris, E., Lazcano, I., Bitterman, P., Basu, S., O’Donnell, J., and Barua. Journal of Immunology Research 2022

Vitamin D mitigates diabetes-associated metabolic and cognitive dysfunction by modulating gut microbiota and colonic cannabinoid receptor 1

Hebatallah M. Hussein, Mohammed F. Elyamany, Laila A. Rashed, Nada A. Sallam European Journal of Pharmaceutical Sciences 2021

Improved cognition impairment by activating cannabinoid receptor type 2: Modulating CREB/BDNF expression and impeding TLR-4/ NFκBp65/M1 microglia signaling pathway in D-galactose-injected ovariectomized rats

Sahar S. Abd El-Rahman, Hany M. Fayed. Plos One 2022

Cannabinoid signalling in the brain

Busquets-Garcia, A.,Melis, M., Bellocchio, L., and Marsicano, G. European Journal of Neuroscience. 2022

Antiseizure Effects of Cannabidiol Leading to Increased Peroxisome Proliferator-Activated Receptor Gamma Levels in the Hippocampal CA3 Subfield of Epileptic Rats

Costa, A.M., Russo, F., Senn, L., Ibatici, D., Cannazza, G., and Biagini, G. Pharmaceuticals 2022

Cannabinoid interventions for improving cachexia outcomes in cancer

Simon, L., Baldwin, C., Kalea, A.Z., and Slee, A. Journal of Cachexia, Sarcopenia and Muscle (2022)

Clinical management of cannabis withdrawal

Connor, J.P., Stjepanovi, D., Budney, A.J., Le Foll, B., and Hall, W.D.   Addiction. 2022 (Article)  

The safety, tolerability, and effectiveness of PTL-101, an oral cannabidiol formulation, in pediatric intractable epilepsy: A phase II, open-label, single-center study

Mitelpunkt, A., Kramer, U., Hausman Kedem, M., Zilbershot Fink, E., Orbach, R., Cheruha, V., Fattal-Valevski, A., Deutsch, L., Heffetz, D., Sacks, H.

Epilepsy & Behavior 2019 (Article)

Single-Dose Pharmacokinetics of Oral Cannabidiol Following Administration of PTL101:A New Formulation Based on Gelatin Matrix Pellets Technology

Atsmon, J., Heffetz, D., Deutsch, L., Deutsch, F., Sacks, H.

Clinical Pharmacology in Drug Development 2017 (Article)

Substitution of medical cannabis for pharmaceutical agents for pain, anxiety, and sleep

Piper BJ, DeKeuster RM, Beals ML, Cobb CM, Burchman CA, Perkinson L, Lynn ST, Nichols SD, Abess AT

Journal of Psychopharmacology 2017 (Article)

Practical Considerations in Medical Cannabis Administration and Dosing

MacCallum CA, Russo EB

European Journal of Internal Medicine Jan 2018 (Article)

Medical Cannabis for Older Patients

Minerbi A, Häuser W, Fitzcharles M-A

Drugs & Aging Nov 2018 (Article)

Medicinal cannabis for psychiatric disorders: a clinically-focused systematic review

Sarris J, Sinclair J, Karamacoska D, Davidson M, Firth J

BMC Psychiatry Jan 2020 (Article)

Considerations for the Use of Medical Cannabis: An Overview of Benefits and Harms

Shakya DR, Upadhaya SR, Neupane H, Subedi R

Biomedical Journal of Scientific & Technical Research Jun 2021 (Article)

Cannabidiol use and effectiveness: real-world evidence from a Canadian medical cannabis clinic

Rapin L, Gamaoun R, El Hage C, Arboleda MF, Prosk E

Journal of Cannabis Research Jun 2021 (Article)

Cannabinoid therapy in epilepsy

Billakota S, Devinsky O, Marsh E

Current Opinion in Neurology Apr 2019 (Abstract)

Medical Cannabis for Intractable Epilepsy in Childhood: A Review

Ben-Zeev B

Rambam Maimonides Medical Journal Jan 2020 (Article)

Cannabis-based products for pediatric epilepsy: An updated systematic review

Elliott J, DeJean D, Clifford T, Coyle D, Potter BK, Skidmore B, Alexander C, Repetski AE, Shukla V, McCoy B, Wells GA

seizure European Journal of Epilepsy Feb 2020 (Article)

Guidance for the use of medicinal cannabis for the prevention or management of nausea and vomiting in Australia

Therapeutic Goods Administration 2017 (Article)

Top Ten Tips Palliative Care Clinicians Should Know About Medical Cannabis

Briscoe J, Kamal AH, Casarett DJ

Journal of Palliative Medicine 2019 (Article)

A critical narrative review of medical cannabis in pediatrics beyond epilepsy, part lll: chemotherapy-induced nausea and vomiting and inflammatory bowel disease

Simonian JS, Varanasi S, Richards GJ, Nguyen AV, Diaz-Fong JP, Le J

Pediatric Medicine 2020 (Article)

Medicinal cannabis: Nausea and Vomiting – Evidence Summary

NPS MedicineWise May 2020 (Article)

Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial

Grimison P, Mersiades A, Kirby A, Lintzeris N, Morton R, Haber P, Olver I, Walsh A, McGregor I, Cheung Y, Tognela A, Hahn C, Briscoe K, Aghmesheh M, Fox P, Abdi E, Clarke S, Della-Fiorentina S, Shannon J, Gedye C, Begbie S, Simes J, Stockler M

Annals of Oncology Nov 2020 (Article)

Medicinal Cannabis in Oncology: a Valuable Unappreciated Remedy or an Undesirable Risk?

Abu-Amna M, Salti T, Idan C, Khoury M, Bar-Sela G

Current Treatment Options in Oncology Feb 2021 (Article)

Medicinal cannabis use in palliative care

Herbert A, Hardy J

Australian Journal of General Practice Jun 2021 (Article)

Medicinal Cannabis Use In Oncology

Bodine M, Kemp AK

StatPearls Internet Jan 2022 (Article)

State of the evidence: Cannabinoids and cancer pain – A Systematic Review

Tateo S

Journal of the American Association of Nurse Practitioners Feb 2017 (Abstract)

A selective review of medical cannabis in cancer pain management

Blake A, Wan BA, Malek L, DeAngelis C, Diaz P, Lao N, Chow E, O’Hearn S

Annals of Palliative Medicine Aug 2017 (Article)

Principles of cancer pain management: An overview and focus on pharmacological and interventional strategies

Yoong J, Poon P

Australian Journal of General Practice Nov 2018 (Article)

Update on cannabis and cannabinoids for cancer pain

Chung M, Kim HK, Abdi S

Current Opinion in Anaesthesiology Dec 2020 (Article)

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

Bíró T, Tóth BI, Haskó G, Paus R, Pacher P

Trends in Pharmacological Sciences Aug 2009 (Abstract)

Medicinal Cannabis in the Palliation of Malignant Wounds – A Case Report

Maida V

Journal of Pain and Symptom Management Oct 2016

Topical Medicinal Cannabis: A New Treatment for Wound Pain – Three Cases of Pyoderma Gangrenosum

Maida V, Corban J

Journal of Pain and Symptom Management Nov 2017 (Article)

Effects of cannabidiol, a cannabis sativa constituent, on oral wound healing

Klein M, De Quadros de Bortolli J, Borghetti RL, Jacoby LS, Salum FG, Cherubini K, Zancanaro de Figueiredo M

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Jan 2020 (Abstract)

Topical cannabis-based medicines – A novel paradigm and treatment for non-uremic calciphylaxis leg ulcers: An open label trial

Maida V, Shi RB, Fazzari FGT, Zomparelli L

International Wound Journal Jul 2020 (Article)

The therapeutic potential of cannabinoids for integumentary wound management

Weigelt MA, Sivamani R, Lev-Tov H

Experimental Dermatology Nov 2020 (Article)

Promoting wound healing of uremic calciphylaxis leg ulcers using topical cannabis-based medicines

Maida V, Shi RB, Fazzari FGT, Zomparelli L

Dermatologic Therapy Nov 2020 (Preview)

A new treatment paradigm for sickle cell disease leg ulcers: Topical cannabis-based medicines

Maida V, Shi RB, Fazzari FGT, Zomparelli L-M

Experimental Dermatology Dec 2020 (Article)

“Less pain with more gain” – Managing wound-related pain with cannabis-based medicines

Maida V, Biasi SA

Wound Repair and Regeneration Jan 2021 (Abstract)

Topical cannabis-based medicines – A novel adjuvant treatment for venous leg ulcers: An open-label trial

Maida V, Shi RB, Fazzari FGT, Zomparelli L

Experimental Dermatology May 2021 (Abstract)

Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis

Lowin T, Straub RH

Arthritis Research & Therapy Sep 2015 (Article)

Cannabis and joints: scientific evidence for the alleviation of osteoarthritis pain by cannabinoids

O’Brien M, McDougall JJ

Current Opinion in Pharmacology Jun 2018 (Abstract)

Medical cannabis and cannabinoids in rheumatology: where are we now?

Sarzi-Puttini P, Batticciotto A, Atzeni F, Bazzichi L, Di Franco M, Salaffi F, Marotto D, Ceribelli A, Ablin JN, Hauser W

Expert Review of Clinical Immunology Oct 2019 (Abstract)

Cannabis Use among Older Persons with Arthritis, Cancer and Multiple Sclerosis: Are We Comparing Apples and Oranges?

Kaskie B, Kang H, Bhagianadh D, Bobitt J

brain sciences Apr 2021 (Article)

Medicinal cannabis for inflammatory bowel disease: real-life experience of mode of consumption and assessment of side-effects

Naftali T, Bar-Lev Schleider L, Sklerovsky Benjaminov F, Lish I, Konikoff FM, Ringel Y

European Journal of Gastroenterology & Hepatology Nov 2019 (Abstract)

Cannabis for the Treatment of Inflammatory Bowel Disease: A True Medicine or a False Promise?

Naftali T, Dor M

Rambam Maimonides Medical Journal Jan 2020 (Article)

Medicinal Cannabis for Inflammatory Bowel Disease: A Survey of Perspectives, Experiences, and Current Use in Australian Patients

Benson MJ, Abelev SV, Connor SJ, Corte CJ, Martin LJ, Gold LK, Suraev AS, McGregor IS

Crohn’s & Colitis 360 Apr 2020 (Article)

Cannabis in Gastroenterology: Watch Your Head! A Review of Use in Inflammatory Bowel Disease, Functional Gut Disorders, and Gut-Related Adverse Effects

Nasser Y, Woo M, Andrews CN

Current Treatment Options in Gastroenterology Nov 2020 (Article)

Inflammatory Bowel Disease and Cannabis: A Practical Approach for Clinicians

Buckley MC, Kumar A, Swaminath A

Advances in Therapy Jun 2021 (Article)

Cannabis, Cannabinoids, and Sleep: a Review of the Literature

Babson KA, Sottile J, Morabito D

Current Psychiatry Reports: Sleep Disorders Mar 2017 (Article)

Medical Cannabis and the Treatment of Obstructive Sleep Apnea: An American Academy of Sleep Medicine Position Statement

Ramar K, Rosen IM, Kirsch DB, Chervin RD, Carden KA, Aurora RN, Kristo DA, Malhotra RK, Martin JL, Olson EJ, Rosen CL, Rowley JA

Journal of Clinical Sleep Medicine Apr 2018 (Article)

Acute effect of vaporized Cannabis on sleep and electrocortical activity

Mondino A, Cavelli M, González J, Santana N, Castro-Zaballa S, Mechoso B, Bracesco N, Fernandez S, Garcia-Carnelli C, Castro MJ, Umpierrez E, Murillo-Rodriguez E, Torterolo P, Falconi A

Pharmacology, Biochemistry and Behavior Feb 2019 (Article)

The use of cannabinoids for sleep: A critical review on clinical trials

Kuhathasan N, Dufort A, MacKillop J, Gottschalk R, Minuzzi L, Frey BN

Experimental and Clinical Psychopharmacology 2019 (Abstract)

Medical cannabis and cannabinoids for impaired sleep: a systematic review and meta-analysis of randomized clinical trials

AminiLari M, Wang L, Neumark S, Adli T, Couban RJ, Giangregorio A, Carney CE, Busse JW

Sleep Feb 2022 (Abstract)

The Clinical Significance of Endocannabinoids in Endometriosis Pain Management

Bouaziz J, Bar On A, Seidman DS, Soriano D

Cannabis and Cannabinoid Research Apr 2017 (Article)

Self-Reported Efficacy of Cannabis for Endometriosis Pain

Reinert AE, Hibner M

Journal of Minimally Invasive Gynecology Nov 2019 (Abstract)

Managing endometriosis pain with cannabis

Schwartz B

Contemporary OB/GYN Dec 2019 (Article)

Cannabis Use, a Self-Management Strategy Among Australian Women With Endometriosis: Results From a National Online Survey

Sinclair J, Smith CA, Abbott J, Chalmers KJ, Pate DW, Armour M

Journal of Obstetrics and Gynaecology Canada Mar 2020 (Abstract)

Endometriosis – an indication for cannabinoids?

Nahler G

Traditional Medicine Jul 2020 (Article)

Cannabinoids and chronic pelvic pain in women: Focus on endometriosis

Marcu I, Gee A, Lynn B

Journal of Endometriosis and Pelvic Pain Disorders Jul 2021 (Abstract)

Medical Cannabis for Neuropathic Pain

Lee G, Grovey B, Furnish T, Wallace M

Current Pain and Headache Reports Feb 2018 (Abstract)

Cannabis products for adults with chronic neuropathic pain

Mücke M, Phillips T, Radbruch L, Petzke F, Häuser W

Cochrane Mar 2018 (Abstract)

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort

Baron EP, Lucas P, Eades J, Hogue O

The Journal of Headache and Pain May 2018 (Article)

Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study

Campbell G, Hall WD, Peacock A, Lintzeris N, Bruno R, Larance B, Nielsen S, Cohen M, Chan G, Mattick RP, Blyth F, Shanahan M, Dobbins T, Farrell M, Degenhardt L

The Lancet Jul 2018 (Article)

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies

Stockings E, Campbell G, Hall WD, Nielsen S, Zagic D, Rahman R, Murnion B, Farrell M, Weier M, Degenhardt L

Pain Oct 2018 (Abstract)

The effectiveness of self-directed medical cannabis treatment for pain

Xiaoxue L, Vigil JM, Stith SS, Brockelman F, Keeling K, Hall B

Complementary Therapies in Medicine Oct 2019 (Abstract)

Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: a prospective cohort study

Capano A, Weaver R, Burkman D

Postgraduate Medicine Nov 2019 (Article)

The pharmacokinetics, efficacy, and safety of a novel selective-dose cannabis inhaler in patients with chronic pain: A randomized, double-blinded, placebo-controlled trial

Almog S, Aharon-Peretz J, Vulfsons S, Ogintz M, Abalia H, Lupo T, Hayon Y, Eisenberg E

European Journal of Pain May 2020 (Article)

No pain, all gain? Interim analysis from a longitudinal, observational study examining the impact of medical cannabis treatment on chronic pain and related symptoms

Gruber SA, Smith RT, Dahlgren MK, Lambros AM, Sagar KA

Experimental and Clinical Psychopharmacology 2021 (Abstract)

Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline

Busse JW, Vankrunkelsven P, Zeng L, Heen AF, Merglen A, Campbell F, Granan L-P, Aertgeerts B, Buchbinder R, Coen M, Juurlink D, Samer C, Siemieniuk RAC, Kumar N, Cooper L, Brown J, Lytvyn L, Zeraatkar D, Wang L, Guyatt GH, Vandvik PO, Agoritsas T

The BMJ Sep 2021 (Article)

Experiences with medical cannabis in the treatment of veterans with PTSD: Results from a focus group discussion

Krediet E, Janssen DGA, Heerdink ER, Egberts TCG, Vermetten E

European Neuropsychopharmacology Jul 2020 (Article)

Short and Long-Term Effects of Cannabis on Symptoms of Post-Traumatic Stress Disorder

LaFrance EM, Glodosky NC, Bonn-Miller M, Cuttler C

Journal of Affective Disorders Sep 2020 (Article)

Evidence for Use of Cannabinoids in Mood Disorders, Anxiety Disorders, and PTSD: A Systematic Review

Stanciu CN, Brunette MF, Teja N, Budney AJ

Psychiatry online Feb 2021 (Abstract)

The Effectiveness of Cannabis Flower for Immediate Relief from Symptoms of Depression

Li X, Diviant JP, Stith SS, Brockelman F, Keeling K, Hall B, Vigil JM

Yale Journal of Biology and Medicine Jun 2020 (Article)

Cannabis and Depression

Feingold D, Weinstein A

Cannabinoids and Neuropsychiatric Disorders Dec 2020 (Abstract)

The Use of Medical Cannabis in the Treatment Comorbid Anxiety and Depression

Mechtler L, Ralyea C, Hart P, Bargnes V

Neurology Apr 2021 (Abstract)

Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

Martin EL, Strickland JC, Schlienz NJ, Munson J, Jackson H, Bonn-Miller MO, Vandrey R

frontiers in Psychiatry Sep 2021 (Article)

Patient-Reported Symptom Relief Following Medical Cannabis Consumption

Stith SS, Vigil JM, Brockelman F, Keeling K, Hall B

frontiers in Pharmacology Aug 2018 (Article)

A naturalistic examination of the perceived effects of cannabis on negative affect

Cuttler C, Spradlin A, McLaughlin RJ

Journal of Affective Disorders Aug 2018 (Article)

Cannabinoid Regulation of Fear and Anxiety: an Update

Papagianni EP, Stevenson CW

Anxiety Disorders Apr 2019 (Article)

Cannabidiol in Anxiety and Sleep: A Large Case Series

Shannon S, Lewis N, Lee H, Hughes S

The Permanente Journal Jul 2019 (Article)

Reduction of Benzodiazepine Use in Patients Prescribed Medical Cannabis

Purcell C, Davis A, Moolman N, Taylor SM

Cannabis and Cannabinoid Research Sep 2019 (Article)

Use of cannabidiol in anxiety and anxiety-related disorders

Skelley JW, Deas CM, Curren Z, Ennis J

Journal of the American Pharmacists Association Jan 2020 (Abstract)

The ”Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders

Ferber Goldstein S, Namdar D, Hen-Shoval D, Eger G, Koltai H, Shoval G, Shbiro L, Weller A

Current Neuropharmacology Feb 2020 (Abstract)

Cannabis use among US adults with anxiety from 2008 to 2017 The role of state-level cannabis legalization

Weinberger AH, Zhu J, Levin J, Barrington-Trimis JL, Copeland J, Wyka K, Kim JH, Goodwin RD

Drug and Alcohol Dependence Sep 2020 (Abstract)

Cannabis, a cause for anxiety? A critical appraisal of the anxiogenic and anxiolytic properties

Sharpe L, Sinclair J, Kramer A, de Manincor M, Sarris J

Journal of Translational Medicine Oct 2020 (Article)

Cannabis use in people with Parkinson’s disease and Multiple Sclerosis: A web-based investigation

Kindred JH, Kaigang L, Ketelhut NB, Proessl F, Fling BW, Honce JM, Shaffer WR, Rudroff T

Complementary Therapies in Medicine Aug 2017 (Abstract)

The Use of Cannabis and Cannabinoids in Treating Symptoms of Multiple Sclerosis: a Systematic Review of Reviews

Nielsen S, Germanos R, Weier M, Pollard J, Degenhardt L, Hall W, Buckley N, Farrell M

Neurology of Systemic Diseases Feb 2018 (Abstract)

Assessment of Efficacy and Tolerability of Medicinal Cannabinoids in Patients With Multiple Sclerosis: A Systematic Review and Meta-analysis

Torres-Moreno MC, Papaseit E, Torrens M, Farre M

JAMA Network Open Oct 2018 (Article)

The dark side of the moon: looking beyond beneficial effects of cannabis use in multiple sclerosis

Penner I-K, Hartung H-P

Brain Sep 2019 (Article)

The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis

Maayah ZH, Takahara S, Ferdaoussi M, Dyck JRB

Inflammation Research Apr 2020 (Abstract)

Patterns of Medical Cannabis Use among Patients Diagnosed with Multiple Sclerosis

Guarnaccia JB, Khan A, Ayettey R, Treu JA, Comeford B, Njike VY

Multiple Sclerosis and Related Disorders May 2021 (Abstract)

Endocannabinoid System and Migraine Pain: An Update

Greco R, Demartini C, Zanaboni AM, Piomelli D, Tassorelli C

frontiers in Neuroscience Mar 2018 (Article)

Short- and Long-Term Effects of Cannabis on Headache and Migraine

Cuttler C, Spradlin A, Cleveland MJ, Craft RM

The Journal of Pain May 2020 (Article)

Migraine Frequency Decrease Following Prolonged Medical Cannabis Treatment: A Cross-Sectional Study

Aviram J, Vysotski Y, Berman P, Lewitus GM, Eisenberg E, Meiri D

Brain Sciences Jun 2020 (Article)

Alleviative effects of Cannabis flower on migraine and headache

Stith SS, Diviant JP, Brockelman F, Keeling K, Hall B, Lucern S, Vigil JM

Journal of Integrative Medicine Sep 2020 (Abstract)

Medical Cannabis, Headaches, and Migraines: A Review of the Current Literature

Poudel S, Quinonez J, Choudhari J, Au ZT, Paesani S, Thiess AK, Ruxmohan S, Hosameddin M, Ferrer GF, Michel J

Cureus Aug 2021 (Article)

The Case for Cannabis: The Evidence for Treating Migraine with Cannabis

Sexton M

Emergency Medicine News Sep 2021 (Article)

Endocannabinoid Signaling in Autism

Chakrabarti B, Persico A, Battista N, Maccarrone M

Neurotherapeutics Jul 2015 (Article)

Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems – A Retrospective Feasibility Study

Aran A, Cassuto H, Lubotzky A, Wattad N, Hazan E

Journal of Autism and Developmental Disorders Oct 2018 (Abstract)

Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy

Schleider LB-L, Mechoulam R, Saban N, Meiri G, Novack V

Scientific Reports Jan 2019 (Article)

Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder

Pretzsch CM, Freyberg J, Voinescu B, Lythgoe D, Horder J, Mendez MA, Wichers R, Ajram L, Ivin G, Heasman M, Edden RAE, Williams S, Murphy DGM, Daly E, McAlonan GM

Neuropsychopharmacology Feb 2019 (Article)

Cannabidiol as a suggested candidate for treatment of autism spectrum disorder

Poleg S, Golubchik P, Offen D, Weizman A

Progress in Neuro-Psychopharmacology and Biological Psychiatry Mar 2019 (Abstract)

Current state of evidence of cannabis utilization for treatment of autism spectrum disorders

Agarwal R, Burke SL, Maddux M

BMC Psychiatry Oct 2019 (Article)

Effects of CBD-Enriched Cannabis sativa Extract on Autism Spectrum Disorder Symptoms: An Observational Study of 18 Participants Undergoing Compassionate Use

Fleury-Teixeira P, Caixeta FV, da Silva LCR, Brasil-Neto JP, Malcher-Lopes R

frontiers in Neurology Oct 2019 (Article)

Autism Spectrum Disorder and Medical Cannabis: Review and Clinical Experience

Mostafavi M, Gaitanis J

Seminars in Pediatric Neurology Oct 2020 (Abstract)

Cannabinoid treatment for autism: a proof-of-concept randomized trial

Aran A, Harel M, Cassuto H, Polyansky L, Schnapp A, Wattad N, Shmueli D, Golan D, Castellanos FX

Molecular Autism Feb 2021 (Article)

Symptoms, adverse events, and outcomes in the use of medicinal cannabis in children and adolescents with autism spectrum disorder: a scoping review protocol

Fletcher S, Pawliuk C, Ip A, Oberlander T, Siden H

JBI Evidence Synthesis May 2021 (Article)

Safety and Efficacy of Medical Cannabis in Autism Spectrum Disorder Compared with Commonly Used Medications

Holdman R, Vigil D, Robinson K, Shah P, Contreras AE

Mary Ann Liebert Inc publishers Aug 2021 (Abstract)

Cannabinoids in Parkinson’s Disease

Bassi MS, Sancesario A, Morace R, Centonze D, Iezzi E

Cannabis and Cannabinoid Research 2017 (Article)

Cannabinoids in the Treatment of Parkinson’s Disease

Gandor F, Ebersbach G

Neurology International Open 2017 (Article)

Cannabis use in people with Parkinson’s Disease and Multiple Sclerosis: A web-based investigation

Kindred JH, Li K, Ketelhut NB, Proessl F, Fling BW, Honce JM, Shaffer WR, Rudroff T

Complementary Therapies in Medicine Aug 2017 (Abstract)

Pros and Cons of Marijuana in Treatment of Parkinson’s Disease

Patel RS, Kamil S, Shah MR, Bhimanadham NN, Imran S

Cureus Jun 2019 (Article)

Neuroprotection or Neurotoxicity of Illicit Drugs on Parkinson’s Disease

Ferreira C, Almeida C, Tenreiro S, Quintas A

Life Jun 2020 (Article)

Weeding through the haze: a survey on cannabis use among people living with Parkinson’s disease in the US

Feeney MP, Bega D, Kluger BM, Stoessl AJ, Evers CM, De Leon R, Beck JC

npj Parkinson’s Disease 2021 (Article)

Cannabidiol in patients with Lennox‐Gastaut syndrome: Interim analysis of an open‐label extension study

Thiele E, Marsh E, Mazurkiewicz‐Beldzinska M, Halford JJ, Gunning B, Devinsky O, Checketts D, Roberts C

Epilepsia Mar 2019 (Article)

Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models

Medical Cannabis and Epilepsy Patra PH, Barker-Haliski M, White HS, Whalley BJ, Glyn S, Sandhu H, Jones N, Bazelot M, Williams CM, McNeish AJ

Epilepsia Feb 2019 (Article)

Survey of Australian psychiatrists’ and psychiatry trainees’ knowledge about and attitudes towards medicinal cannabinoids

Jacobs NI, Montebello M, Monds LA, Lintzeris N

Australasian Psychiatry Feb 2019 (Abstract)

Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder

Pretzsch CM, Freyberg J, Voinescu B, Lythgoe D, Horder J, Mendez MA, Wichers R, Ajram L, Ivin G, Heasman M, Edden RAE, Williams S, Murphy DGM, Daly E, McAlonan GM

Neuropsychopharmacology Feb 2019 (Abstract)

Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder

Dale T, Downs J, Olson H, Bergin AM, Smith S, Leonard H

Epilepsy Research Feb 2019 (Abstract)

Efficacy of cannabinoids in paediatric epilepsy

Ali S, Scheffer IE, Sadleir LG

Developmental Medicine & Child Neurology Jan 2019 (Abstract)

Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

Bonini SA, Premoli M, Tambaro S, Kumar A, Maccarinelli G, Memo M, Mastinu A

Journal of Ethnopharmacology Dec 2018 (Abstract)

The Anti-Inflammatory Properties of Terpenoids from Cannabis

Gallily R, Yekhtin Z, Hanuš LO

Cannabis and Cannabinoid Research Dec 2018 (Article)

Cannabis, from plant to pill

Christopher P. L. Grof

British Journal of Clinical Pharmacology Nov 2018 (Article)

Cannabis contaminants: sources, distribution, human toxicity and pharmacologic effects

Laura M. Dryburgh, Nanthi S. Bolan, Christopher P.L. Grof, Peter Galettis, Jennifer Schneider, Catherine J. Lucas and Jennifer H. Martin

British Journal of Clinical Pharmacology Nov 2018 (Article)

Medical cannabis: aligning use to evidence‐based medicine approach

Lihi Bar‐Lev Schleider, Ran Abuhasira and Victor Novack

British Journal of Clinical Pharmacology Nov 2018 (Article)

The pharmacokinetics and the pharmacodynamics of cannabinoids

Catherine J. Lucas, Peter Galettis and Jennifer Schneider

British Journal of Clinical Pharmacology Nov 2018 (Article)

Therapeutic Use of medicinal cannabis in difficult to manage epilepsy

John A Lawson and Ingrid E Scheffer

British Journal of Clinical Pharmacology Nov 2018 (Article)

Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and Meta-Analysis

Lattanzi S, Brigo F, Trinka E, Zaccara G, Cagnetti C, Del Giovane C, Silvestrini M.

Drugs Nov 2018 (Abstract)

Cannabis Therapeutics and the Future of Neurology

Russo EB

Frontiers in Molecular Neuroscience Oct 2018 (Article)

Efficacy and Safety of Adjunctive Cannabidiol in Patients with Lennox-Gastaut Syndrome: A Systematic Review and Meta-Analysis

Lattanzi S, Brigo F, Cagnetti C, Trinka E and Silvestrini M

CNS Drugs Oct 2018 (Abstract)

Medicinal cannabis in Australia,2016 : the Cannabis as Medicine Survey (CAMS-16)

Nicholas Lintzeris, Jessica Driels, Natalie Elias, Jonathon C Arnold, Iain S McGregor and David J Allsop

Medical Journal of Australia Sep 2018 (Article)

Open-label use of highly purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes

Devinsky O, Verducci C, Thiele EA, Laux LC, Patel AD, Filloux F, Szaflarski JP, Wilfong A, Clark GD, Park YD, Seltzer LE, Bebin EM, Flamini R, Wechsler RT and Friedman D

Epilepsy & Behavior Sep 2018 (Article)

Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results

Szaflarski JP, Bebin EM, Comi AM, Patel AD, Joshi C, Checketts D, Beal JC, Laux LC, De Boer LM, Wong MH, Lopez M, Devinsky O, Lyons PD, Zentil PP and Wechsler R

Epilepsia Aug 2018 (Article)

Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents – an observational, longitudinal study

Hausman-Kedem M, Menascu S, Kramer U.

Brain and Development Aug 2018 (Abstract)

Effectiveness of Raw, Natural Medical Cannabis Flower for Treating Insomnia under Naturalistic Conditions

Vigil JM, Stith SS, Diviant JP, Brockelman F, Keeling K, Hall B

Medicines Jul 2018 (Article)

Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community

A. Suraev, N. Lintzeris, J. Stuart, R. C. Kevin, R. Blackburn, E. Richards, J. C. Arnold, C. Ireland, L. Todd, D. J. Allsop & I. McGregor

Scientific Reports Jul 2018 (Article)

Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model

Khan AA, Shekh-Ahmad T, Khalil A, Walker MC, Ali AB.

British Journal of Pharmacology Jun 2018 (Abstract)

Biphasic effects of THC in memory and cognition

Calabrese EJ, Rubio-Casillas A

European Journal of Clinical Investigation May 2018 (Abstract)

Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome

Devinsky O, Patel AD, Cross JH, Villanueva V, Wirrell EC, Privitera M, Greenwood SM, Roberts C, Checketts D, Van Landingham KE and Zuberi SM

New England Journal of Medicine May 2018 (Abstract)

Medicinal Cannabis and the Tyranny of Distance: Policy Reform Required for Optimizing Patient and Health System Net Benefit in Australia

David Caldicott, Justin Sinclair, Lynnaire Sheridan and Simon Eckermann

Applied Health Economics and Health Policy Apr 2018 (Article)

Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome

Devinsky O, Patel AD, Thiele EA, Wong MH, Appleton R, Harden CL, Greenwood S, Morrison G and Sommerville K

Neurology Apr 2018 (Article)

Practical considerations in medical cannabis administration and dosing

MacCallum CA, Russo EB

European Journal of Internal Medicine Mar 2018 (Article)

Evidence for cannabis and cannabinoids for epilepsy: a systematic review of controlled and observational evidence

Emily Stockings, Dino Zagic, Gabrielle Campbell, Megan Weier, Wayne D Hall, Suzanne Nielsen, Geoffrey K Herkes, Michael Farrell, Louisa Degenhardt

Journal of Neurology & Neurosurgical Psychiatry Mar 2018 (Article)

Pharmacogenetics of Cannabinoids

Hryhorowicz S, Walczak M, Zakerska-Banaszak O, Słomski R, Skrzypczak-Zielińska M

European Journal of Drug Metabolism and Pharmacokinets Feb 2018 (Article)

Delta-9-Tetrahydrocannabinol (∆9-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats

Suliman NA, Taib CNM, Moklas MAM, Basir R

Neurotoxicity Research Feb 2018 (Article)